New paradigms in the management of hemoglobinopathies - 2021 update

Acquisizione competenze di sistema:Discuss various updates in disease understanding and management for patients with hemoglobinopathies. Emerging insights on molecular pathways and clinical forms will be discussed. These would then lead the way to an overview and deep interpretation of novel data clinical trials of bone marrow transplant, gene therapy, genome editing, and other agents that target the ineffective erythropoiesis and iron dysregulation in thalassemia, as well as sickling, hemolysis and vasculopathy in sickle cell disease. sharing experiences on managing patients with hemoglobinopathies during the covid-19 pandemic.